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Nature Made Cholest-Off Plus, 450 mg - 200 Softgels

CholestOff® Plus is made with Reducol™ a proprietary blend of plant sterols and stanols (also called phytosterols). Sterols and stanols work to help block cholesterol absorption and reduce LDL (bad) cholesterol in the bloodstream.  Along with a diet low in saturated fat and cholesterol, CholestOff Plus is an option as part of a cholesterol management program.


•Clinically proven to lower cholesterol.*
•Take 2 softgels twice daily with meals.
•Is a safe and effective part of a cholesterol management program.

How do plant sterols and stanols work to help block cholesterol absorption and reduce LDL (bad) cholesterol in the bloodstream?

Plant sterols and stanols, also referred to as the phytosterols, are plant-derived compounds that are similar in structure to cholesterol. Plant sterols and stanols competitively help block the absorption of cholesterol in the digestive tract. As a result of this, the sterols and stanols help prevent dietary cholesterol absorption and reduce LDL (“bad”) cholesterol.

How does CholestOff Plus Work?

The dietary supplement form of phytosterols provides a convenient, easy to take supplement and offers approximately 1.8 grams (g) of phytosterols per day with a negligible amount of calories. Because many Americans consume as little as about 200 mg per day, this is the amount many Americans need to reach the 2,000 mg per day recommended by the National Institute of Health (NIH) Therapeutic Lifestyle Changes Guidelines.

What are the food sources of plant sterols and stanols?

Plant sterols and stanols occur naturally in small amounts in plant-based foods such as unrefined vegetable oils, whole grains, nuts and legumesΔ. However, in order to meet the recommended guidelines for cholesterol reduction through un-fortified food alone, one would need to consume an excessive amount of these foods to obtain the recommended 2 grams of sterols and stanols.

* Products containing at least 400 mg per serving of plant sterols and stanols, eaten twice a day with meals for a daily intake of at least 800 mg as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease. One serving of Nature Made CholestOff supplies 900 mg of plant sterols and stanols per serving for a daily intake of 1800 mg.

Δ CholestOff is sourced from Pine Trees

Suggested Use: Take two softgels two times daily with meals.


Caution: Not for use by pregnant or lactating women or children. Check with your physician before using CholestOff Plus if you are currently using medications to lower your cholesterol.


Color Derived from Natural Source- No Synthetic Dyes. No Artificial Flavors. No Preservatives. No Yeast, Starch or Gluten. 


Keep out of reach of children.


For Consumer Questions or Inquiries call 1-800-276-2878 or visit www.naturemade.com


‡ Sterols/Stanols are esterified with sunflower oil fatty acids.

ingredients: Plant Sterols/Stanols (Pine Tree), Sunflower Oil Esters, Gelatin, Glycerin, Medium Chain Triglycerides, Soy Lecithin, Water, Colors Added. 

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