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Dr. Whitaker's Pycnogenol Clinical Grade - 60 capsules

Help Maintain the Health of Your Joints, Vision, Ears, Heart, Brain, and Skin with Clinical Grade Pycnogenol More clinical studies! More versatile health applications! A powerful antioxidant to address the health of your skin, eyes, ears, joints, brain, heart—and more!

For years now I've been recommending Pycnogenol® (pic-noj-en-all) French Maritime Pine Extract for its numerous health benefits. And I'm not alone in praising this versatile superstar nutrient. Over the past two decades, 340 scientific publications and more than 130 clinical trials have revealed the beneficial effects of Pycnogenol for your joints, eyes, ears, heart and skin health. In fact, it is one of the most well-researched, branded ingredients available on the market—if not the most researched.

Pycnogenol is a patented extract of maritime pine bark, grown exclusively in the pristine Les Landes de Gascogne forest of southwest France. There are other generic "pine bark" extracts out there. However, Pycnogenol is the only pine bark extract shown in extensive human clinical studies to have remarkable benefits for such a wide variety of health needs.

Nature's Super Antioxidant

Pycnogenol—considered a super antioxidant—has been clinically studied and shown to support the function of the endothelium (the innermost layer of cells lining the blood vessels) and promote a proper inflammatory response. When cells are damaged—either from injury or free-radical oxidation—inflammation occurs. Fortunately, Pycnogenol is an extremely powerful antioxidant that counters oxidative stress and increases the activity of vitamin C, glutathione, and other antioxidants. Addressing oxidative stress before it starts allows blood vessels to function optimally. At varying dosages, Pycnogenol supports the health of your skin, eyes, ears, and joints, and aids in blood sugar support and normal cognitive, sexual, circulatory, and vascular function. Adjust your dose of Pycnogenol depending on your own health concerns 1. Vascular and Circulatory Health (150–200 mg/daily)

In addition to its powerful antioxidant properties, Pycnogenol also helps increase levels of nitric oxide (NO). NO is an important signaling molecule in cells throughout the body. Produced in the endothelial cells lining the blood vessels, NO protects the blood vessels and dilates the smooth muscles of the small arteries that regulate blood flow and blood pressure. Therefore, Pycnogenol not only helps strengthen the blood vessel walls and capillaries but also supports healthy circulation.

2. Blood Pressure and Blood Sugar Health (150 mg/daily)

Pycnogenol's positive effects on NO production and endothelial function help promote normal blood pressure. But research reveals that this versatile nutrient also supports optimal blood sugar metabolism.

In a randomized, double-blind, placebo-controlled study, individuals were given 125 mg of Pycnogenol or a placebo daily. Supplementation with Pycnogenol helped promote healthy blood pressure levels, with statistically significant reductions in markers of blood vessel constriction. What's more, because Pycnogenol slows the breakdown of starch in the intestines and the rate of glucose absorption, improvements were noted in blood sugar support, including lower levels of fasting glucose.1

3. Joint Health (200 mg/daily)

As we age, our joints tend to work less effectively. When joint space is reduced and cartilage no longer provides the structure and support needed for easy movement, it sets off an inflammatory reaction and causes the levels of C-reactive protein (CRP), a marker of inflammation, to increase. Pycnogenol helps provide a proper inflammatory response. In clinical trials, Pycnogenol has been shown to lower CRP and promote healthy knee function.

In a double-blind, placebo-controlled study, individuals taking 200 mg/daily of Pycnogenol had significant improvements in joint discomfort, function, and performance on a treadmill.2 In another clinical study, Pycnogenol lowered CRP by 72%, while only an 8% reduction was observed with the placebo.3

4. Hearing and Ear Health (150 mg/daily)

Ringing in the ears can be a common and annoying problem related to normal aging. But maintaining the health of the blood vessels and supporting proper circulation in the inner ear can help. Because Pycnogenol boosts NO production and promotes proper blood flow, it helps microcirculation to the cochlea (the hearing center), which may reduce occasional ringing and support the overall health of your inner ear.

In a six-month study at the Chieti-Pescara University in Italy, a group of individuals took 150 mg/daily of Pycnogenol or a placebo. When they were retested after three and six months, individuals taking Pycnogenol had significant improvement in inner ear blood flow, compared to the placebo group.4 At three months, 45% of those taking Pycnogenol had improvements in occasional ringing in the ears compared with 23% in the control group.5

5. Vision and Retinal Health (150–200 mg/daily)

Supporting vision is especially important as we age and Pycnogenol shines when it comes to promoting eye health. Pycnogenol supports healthy retinal blood vessels and microcirculation in the retina.

In a three-month study, individuals who took Pycnogenol had 30% greater improvements in retinal blood flow compared to those taking the placebo. Pycnogenol also improved scores of dilated ophthalmology (a measure of retinal swelling), visual acuity, and retinal thickness.6

6. Skin Health (50–300 mg/daily)

Like other organs, your skin depends on healthy blood vessels and robust blood flow to deliver antioxidants and other nutrients and maintain optimal function. Pycnogenol generates NO, which relaxes the blood vessels and consequently allows for healthy blood flow to the skin. Pycnogenol's potent antioxidant and anti-inflammatory activity reduces inflammation for proper skin elasticity and smoothness.

In a four-week, placebo-controlled study, participants who took 100–200 mg/daily of Pycnogenol had significant reductions in redness of the skin due to inflammation, compared to those taking a placebo. A parallel in vitro study indicated that Pycnogenol does this by inhibiting markers of inflammation.7

7. Cognitive Health, Including Mental Performance and Attention (150 mg/daily)

Increased levels of NO are also beneficial for cognitive health. NO is synthesized in the brain, where it functions as a neurotransmitter and is involved in memory and learning. Pycnogenol, which boosts levels of NO, helps support mental performance, attention, and overall cognitive function.

In a recent Pycnogenol study in the Journal of Neurosurgical Sciences, 150 mg a day of Pycnogenol was shown to support mental performance, attention, and memory; improve mood; and reduce oxidative stress by 30%.8

Clinical grade Pycnogenol is my number one trusted source of pine bark, and the only one I recommend at the Whitaker Wellness Institute. No other nutrient can do more for so many health concerns. For these reasons and more, you'll find Pycnogenol in my Ocular Pressure & Retina Defense™ and Nitric Oxide CardioBoost™ formulas, as well as my recommended product for men's sexual health, Prelox®. And this standalone formula allows you to easily adjust your dose depending on your own health needs.

Doctor's Suggested Use: Take 1 or more capsules daily.

Ingredients and Dosage

Doctor's Suggested Use: Take 1 or more capsules daily.

Serving Size: 1 Capsule Servings Per Container: 60

Ingredient Amount Per Serving % DV
Pycnogenol® French Maritime Pine Extract (bark) 50 mg *
* Daily Value (DV) not established

Other ingredients: Maltodextrin, gelatin, magnesium stearate, silicon dioxide

Note: Pregnant or lactating women should consult a health care professional before taking this product. Keep out of reach of children.

Pycnogenol® is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

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